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KMID : 1094020140310030226
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Journal of Veterinary Clinics
2014 Volume.31 No. 3 p.226 ~ p.232
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CNS Relapsed T-cell Lymphoma in a Young Cat
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Seo Kyoung-Won
Oh Ye-In
Han Sei-Myoung
Go Du-Min
Lee Jeong-Ha
Youn Hwa-Young
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Abstract
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An 8-month-old domestic shorthair cat presented with decreased activity and anorexia. Diagnostic imagingrevealed cranial mediastinal mass and enlarged mesenteric lymph nodes. Fine needle aspirates showed a marked increasein malignant lymphocytes. Multicentric lymphoma (stage V-b) was diagnosed. The cat treated with COP protocolchemotherapy, and complete remission was induced. CNS relapse developed 314 days after the initiation ofchemotherapy. Treatment with rescue protocol greatly reduced the clinical signs for a short period. The cat was inpartial remission for 33 days and overall survival time was 383 days. Multicentric T-cell lymphoma with braininvolvement was confirmed after necropsy by histopathology and immunohistochemistry.
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KEYWORD
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cat, central nervous system, cytarabine (cytosine arabinoside), relapsed lymphoma
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